Fig. 6

ω-3 fatty acids was partly disabled after MCAO/R. a TTC-stained coronal sections from representative animals at 72 h after reperfusion. b Statistical analysis of infarct volume. Reproducible infarct volumes were observed in the MCAO/R + vehicle group, MCAO/R + ω-3 group, and MCAO/R + RvD2 group. The infarct volume is expressed as a percentage of the ipsilateral hemispheric volume. Data are means ± SEM. **P < 0.01 vs. sham group, ^#P < 0.05, ^$P < 0.05, ^&P < 0.05, n = 6. c RvD2 production after supplying ω-3 fatty acids and injection of RvD2 was detected by ELISA. Data are means ± SEM, n = 6. **P < 0.01 vs. sham group, ^#P < 0.05, ^&P < 0.05, ^%P < 0.05, ^$$P < 0.01. N.S. = no significant differences. d Western blot analysis was used to detect the protein levels of 5-LOX and Phos-5-LOX after I/R brain injury. Quantification of the Phos-5-LOX/5-LOX level is shown (e). Data are presented as mean ± SEM, n = 6. **P < 0.01, ***P < 0.001 vs. sham group, ^&P < 0.05, N.S. = no significant differences