Fig. 8
From: Resolvin D2 protects against cerebral ischemia/reperfusion injury in rats
Animal groups. a The first experiment was designed to show the time course of the protein level of 5-LOX, phosphorylation of 5-LOX, and levels of endogenous RvD2 after MCAO/R and identify the suitable time point for the second experiment. b The second experiment was designed to observe the effects of intervention with exogenous RvD2 at different doses on I/R brain injury after MCAO/R in SD rats. c The third experiment was designed to identify the potential mechanisms of the alleviation of I/R-brain injury by RvD2. d The fourth experiment was designed to compare the effects of RvD2 on I/R with those of ω3-polyunsaturated fatty acids in vivo