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Table 3 The detailed information of top 30 up-regulated and 30 down-regulated mRNAs

From: Identification of lncRNA expression profiles and ceRNA analysis in the spinal cord of morphine-tolerant rats

Gene symbol Description Fold change(MT/NS) P-value
Up-regulated genes
 RT1-Bb RT1 class II, locus Bb 26.0600137 0.03123893
 RatNP-3b defensin RatNP-3 precursor 4.6945682 0.00237615
 Lilrb3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 4.3359795 0.00815228
 Defa7 alpha-defensin 7 4.2552547 0.00156229
 Clecsf9 macrophage-inducible C-type lectin 3.4622832 0.01864872
 Ccl7 chemokine (C-C motif) ligand 7 3.3728046 0.01483951
 Sele selectin, endothelial cell 3.3632425 0.03028204
 Slpi secretory leukocyte peptidase inhibitor 3.2118152 0.00024306
 Lilrc2 leukocyte immunoglobulin-like receptor 3.1471364 0.01375120
 V1rj4 vomeronasal 1 receptor, J4 2.9047312 0.03220865
 Gja5 gap junction membrane channel protein alpha 5 2.8707048 0.02230140
 Mmp9 matrix metallopeptidase 9 2.832538 0.02991875
 Batf basic leucine zipper transcription factor 2.7432184 0.00125327
 S100a8 S100 calcium binding protein A8 (calgranulin A) 2.7009035 0.00561932
 Birc3 baculoviral IAP repeat-containing 3 2.6968995 0.01058921
 Bcl3 B-cell CLL/lymphoma 3 2.6847827 0.00419171
 Ccr1 chemokine (C-C motif) receptor 1 2.5775393 0.00007731
 Olr463 olfactory receptor 463 (predicted) 2.5772986 0.01425058
 Np4 defensin NP-4 precursor 2.4883044 0.00271115
 Grm2 glutamate receptor, metabotropic 2 2.4429944 0.00113554
 Slpil2 antileukoproteinase-like 2 2.4380328 0.00066484
 Cnn1 calponin 1 2.4269788 0.02918954
 Olr139 olfactory receptor Olr139 2.4268332 0.01332394
 Obp3 alpha-2u globulin PGCL4 2.3723118 0.03995990
 Crisp4 cysteine-rich secretory protein 4 2.3633549 0.00810051
 Olr1454_predicted olfactory receptor 1454 (predicted) 2.3350625 0.00247670
 Napsa napsin A aspartic peptidase 2.2770041 0.00035275
 Olr1374_predicted olfactory receptor 1374 (predicted) 2.2313479 0.00040213
 LOC497796 Ly49 inhibitory receptor-like 2.2302475 0.00022859
 Slpil3 antileukoproteinase-like 3 2.2153032 0.00045886
Down-regulated genes
 Fam111a hypothetical protein LOC499322 5.1287218 0.02433528
 Kcnv2 “potassium channel, subfamily V, member 2” 2.8837136 0.00586212
 Fkbp6 FK506 binding protein 6 2.8648794 0.00576975
 Nlrp10 “NLR family, pyrin domain containing 10” 2.6101210 0.00386452
 Rgs1 regulator of G-protein signaling 1 2.4933037 0.00327101
 Ly49i8 Ly49 inhibitory receptor 8 2.3732515 0.01051908
 Tmem119 transmembrane protein 119 2.3374630 0.00064129
 Cldn14 Rattus norvegicus claudin 14” 2.3184480 0.00751794
 Dyrk1a dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 2.2472669 0.00077705
 Ckmt2 sarcomeric mitochondrial creatine kinase 2.2142101 0.00051314
 Asb2 ankyrin repeat and SOCS box-containing protein 2 2.1709796 0.00039719
 Art2b ADP-ribosyltransferase 2b 2.1680042 0.00124959
 LOC498335 similar to Small inducible cytokine B13 precursor (CXCL13) 2.1501415 0.00012158
 Prrx2 paired related homeobox 2 2.1294428 0.01452534
 LOC364773 aldo-keto reductase family 1, member C12 2.1023343 0.00302323
 Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 2.0882944 0.00336651
 Cd22 CD22 molecule 2.0855279 0.01215534
 Nhlrc2 NHL repeat containing 2 2.0426710 0.00054605
 Fcrls Fc receptor-like S, scavenger receptor 2.0407116 0.00627688
 Clca3 chloride channel calcium activated 3 2.0188429 0.01580260
 Dntt deoxynucleotidyltransferase, terminal 2.0019106 0.00547055
 Grap2 GRB2-related adaptor protein 2 1.9900082 0.00968363
 Thrsp thyroid hormone responsive protein 1.9814822 0.02740488
 Plek2 pleckstrin 2 1.9662998 0.00879852
 Alox12 arachidonate 12-lipoxygenase 1.9121487 0.00631083
 Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 1.8804698 0.00229007
 Mpzl2 myelin protein zero-like 2 1.8783013 0.00003750
 Prkag3 protein kinase, AMP-activated, gamma 3 1.8643095 0.00970172
 Nr0b2 nuclear receptor subfamily 0, group B, member 2 1.8348501 0.00251892
 Traf3ip3 TRAF3 interacting protein 3 1.8326037 0.02787730