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Table 3 Comprehensive behavioral test battery of Rapgef6-KO mice

From: Comprehensive behavioral analysis of mice deficient in Rapgef2 and Rapgef6, a subfamily of guanine nucleotide exchange factors for Rap small GTPases possessing the Ras/Rap-associating domain

Test

Age (w)

1. General health

14–16

2. Rotarod

20–22

3. Hot plate

18–19

4. Open field

15–17

5. Light/dark transition

15–16

6. Elevated plus-maze

17–19

7. Porsolt forced swim

32–34

8. Tail suspension test

41–42

9. Prepulse inhibition

32–33

10. Social Interaction (novel environment)

19–20

11. Social Interaction (home cage)

59–62

12. Social Interaction (Crawley version)

31–33

13. Barnes maze (training)

32–36

14. Barnes maze (probe test (24 h))

34–36

15. Barnes maze (probe test (1 month))

39–40

16. T-maze (forced alternation without fasting)

39–42

17. Fear conditioning test (Day 1)

41–43

18. Fear conditioning test (Day 2)

41–43

19. Fear conditioning test (Day 36)

46–48

  1. Age (w) age in weeks of mice at the beginning of each test listed