Fig. 2

Reduced GABAergic postsynaptic components in the hippocampus of NL2 R215H KI mice. a Representative images of gephyrin, GABA_A receptor γ2 subunit and merged immunostaining in the granule cell layer of WT and R215H KI mice. b, c Quantification of gephyrin puncta number and size at granule cell soma region. d, e Quantification of γ2 puncta number and size at the same region as gephyrin. WT = 9 slices from 3 mice, R215H KI = 12 slices from 3 mice. Scale bar = 10 μm. Student’s t-test was used for analysis and data were shown as Mean ± SEM, *P < 0.05, **P < 0.01, ***P < 0.001