Fig. 2
From: DNMT1 regulates expression of MHC class I in post-mitotic neurons
Knockdown of DNMT1 increases MHC-I gene expression in post-mitotic mouse CGNs. Shown is the fold change in gene expression of DNMT1 (a), DNMT3a (b), DNMT3b (c), β2M (d), H2-D1 (e), and H2-D1/L (f) following 72 h siRNA treatment of CGN cultures. Baseline indicate gene expression level in untreated CGNs. Bars represent mean +/− S.E.M., N = 8 from three independent experiments. Stars illustrate effects that are significantly different from untreated CGNs, unless otherwise indicated. * p < 0.05, *** p < 0.001, multiplicity corrected p-values in a Two-Way ANOVA with Dunnett’s post hoc test