Fig. 7
From: DNMT1 regulates expression of MHC class I in post-mitotic neurons
CGNs with high uptake of siRNA against DNMT1 do not express MHC-I protein. MHC-I/H2 (green), Cy3-labeled siRNA against DNMT1 (red), and β-III-tubulin (pink) were detected by immunofluorescence performed on untreated CGNs (a), CGNs treated with IFNγ (b), and CGNs treated with Cy3-labeled siRNA targeting DNMT1 (c). Arrow indicates colocalizing Cy3-labeled siRNA targeting DNMT1 and β-III-tubulin (neuron with high uptake of siRNA targeting DNMT1). Scale bar, 10 μm