Fig. 6
From: Chronic restraint stress induces hippocampal memory deficits by impairing insulin signaling
Prevention of CRS-induced hippocampal insulin signaling impairment and autophagy by intranasal insulin delivery. a Western blotting analysis of the insulin signaling pathway and the characteristics of cell death in the mouse hippocampus. b Quantification of each insulin signaling molecules analyzed by two-way ANOVA (IRβ, n = 9; GR, n = 7; p-IRS-Y608, n = 13; p-Akt-S473 n = 10; p-mTOR-S2448, n = 7). c Quantification of LC3-II analyzed by two-way ANOVA (n = 5 per group). d Quantification of C.Casp-3 analyzed by two-way ANOVA (n = 4 per group). Data are mean ± SEM. ***p < 0.001