Fig. 4

Effects of riluzole on isolated leak K⁺ currents at different temperatures in acutely dissociated small-sized DRG neurons of rats. a–c Three sets of sample traces show isolated leak K⁺ currents at 14 °C (a), 22 °C (b) and 30 °C (c). In each set of overlaying traces, gray line is isolated leak K⁺ current in the absence and black line is isolated leak K⁺ current in the presence of 100 μM riluzole. d Summary data of the amplitudes of isolated leak K⁺ currents at different temperatures in the absence (control, open bars) and present of 100 μM riluzole (closed bars, n = 14). e Summary data of the normalized amplitudes of isolated leak K⁺ currents at different temperatures in the absence (control, open bars) and present of 100 μM riluzole (closed bars, n = 14). In all recordings, leak K⁺ currents were induced by voltage steps from − 74 mV to 34 mV. Data represent Mean ± SEM, *p < 0.05, **p < 0.01, comparing between controls and in the presence of riluzole, two-way ANOVA