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Table 1 Mice sacrifice at different EAE stages

From: The ion channel TRPM4 in murine experimental autoimmune encephalomyelitis and in a model of glutamate-induced neuronal degeneration

  Day of sacrifice Average clinical score EAE stage
Mice 1–3 Day 8 0 Immune activation but no EAE symptoms
Mice 4–6 Day 11 0.5 Weight loss and very early EAE symptoms
Mice 7–10 Day 14 1.5 Confirmed EAE symptoms
Mice 11–14 Day 18 2.5 EAE peak
Mice 15–18 Day 28 2.0 Chronic EAE symptoms