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Table 1 Mice sacrifice at different EAE stages

From: The ion channel TRPM4 in murine experimental autoimmune encephalomyelitis and in a model of glutamate-induced neuronal degeneration

 

Day of sacrifice

Average clinical score

EAE stage

Mice 1–3

Day 8

0

Immune activation but no EAE symptoms

Mice 4–6

Day 11

0.5

Weight loss and very early EAE symptoms

Mice 7–10

Day 14

1.5

Confirmed EAE symptoms

Mice 11–14

Day 18

2.5

EAE peak

Mice 15–18

Day 28

2.0

Chronic EAE symptoms