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Fig. 3 | Molecular Brain

Fig. 3

From: Dysregulation of human NEFM and NEFH mRNA stability by ALS-linked miRNAs

Fig. 3

MiRNAs that have MREs within NEFM or NEFH 3’UTRs are expressed in motor neurons of human spinal cord control tissue. FISH was performed using FFPE control spinal cord tissue and LNA™-enhanced detection probes 5’-DIG and 3’-DIG labeled for miRNAs. Amplification was performed using anti-DIG-HRP and TSA Plus Cy3. MiR-548c-3p, which is not expressed in human spinal cord, was used as negative control. MiR-124-3p, which is known as highly expressed in neurons, was used as positive control

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