Fig. 4

Chromatin appeared non-clustered in fast perfusion-fixed mouse brains where neurons are under a basal state (a, c), but aggregated into dark clusters in delayed perfusion-fixed brains where neurons are under excitatory stress (b, d). Samples were from the CA1 region of the hippocampus (a, b) and layer III of cerebral cortex (c, d). Scale bar = 0.5 μm