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Table 1 Effect of depolarization with high K+ on number of ER cisternal stacks in neuronal somas in slice cultures, expressed as number per 100 neuronal somas

From: Stimulation-induced structural changes at the nucleus, endoplasmic reticulum and mitochondria of hippocampal neurons

Exp

Cont

30″ K+

1′ K+

2′ K+

3′ K+

5′ K+

K+ + 1′ rec

K+ + 2′ rec

K+ + 5′ rec

K+ + 10′ rec

K+ + 1 h rec

1

0 (23)

14 (21)

 

241 (22)

 

659 (17)

     

2

0 (21)

   

376 (21)

      

3

0 (14)

   

167 (21)

 

305 (21)

 

20 (15)

  

4

0 (22)

   

327 (22)

    

0 (27)

0 (24)

5

0 (19)

 

10 (21)

    

85 (13)

   

6

0 (21)

 

57 (23)

   

55 (20)

 

0 (17)

  

Mean ± SEM

0

27 ± 15

278 ± 46

 

7 ± 7

 
  1. Statistical analysis by ANOVA with Tukey’s post-test: data points from 30″ and 1′ K+, 2–3′ K+, and 5–10′ recovery were pooled, respectively (mean values of each listed in the last row). 2–3′K+ is highly significant over other conditions (P < 0.0001 vs. cont, 30′-1′K+, 5–10′ rec). Not significant among all other multiple comparisons including cont, 30′-1′K+ and 5–10′ rec
  2. (n) number of somas examined
  3. rec recovery in control medium
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Molecular Brain

ISSN: 1756-6606