Fig. 2
From: Control of occlusion of middle cerebral artery in perinatal and neonatal mice with magnetic force
Producing focal occlusion in perinatal and neonatal mouse brains with SIMPLE. a. Schematic illustration of the location of the micro-magnet and the site of MP injection. b. MP aggregation (arrows) in blood vessels of multiple P3 mice at different time points (10 min, 0.5 h, 1 h, 2 h, 4 h and 17 h; MP dose, 100 μg/g). Right panel, higher magnification image of MP occlusion in a P3 mouse brain after 10 min SIMPLE. c. MP aggregation after 10 min SIMPLE in a P7 mouse brain. Inset, high-magnification image of pial vessels occluded with MPs (white arrow). d. FJC staining of a brain section from a P3 mouse that was subjected to 24 h SIMPLE. (a’–c’) Insets from (d), indicating regions of non-infarct control region (a’), peri-infarct region (b’), and infarct region (c’)