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Fig. 2 | Molecular Brain

Fig. 2

From: Control of occlusion of middle cerebral artery in perinatal and neonatal mice with magnetic force

Fig. 2

Producing focal occlusion in perinatal and neonatal mouse brains with SIMPLE. a. Schematic illustration of the location of the micro-magnet and the site of MP injection. b. MP aggregation (arrows) in blood vessels of multiple P3 mice at different time points (10 min, 0.5 h, 1 h, 2 h, 4 h and 17 h; MP dose, 100 μg/g). Right panel, higher magnification image of MP occlusion in a P3 mouse brain after 10 min SIMPLE. c. MP aggregation after 10 min SIMPLE in a P7 mouse brain. Inset, high-magnification image of pial vessels occluded with MPs (white arrow). d. FJC staining of a brain section from a P3 mouse that was subjected to 24 h SIMPLE. (a’c’) Insets from (d), indicating regions of non-infarct control region (a’), peri-infarct region (b’), and infarct region (c’)

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