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Fig. 2 | Molecular Brain

Fig. 2

From: Plasticity changes in forebrain activity and functional connectivity during neuropathic pain development in rats with sciatic spared nerve injury

Fig. 2

Nerve transection device. (a) Photograph of the nerve transection device, which consists of a guidance head and needle with fork tips, and was implanted before MRI scanning (A-1). A stainless steel wire (A-2) was threaded through the needle, and fixed the common peroneal and tibial nerves (A-3) to the notches of the fork tips by using a slack noose. (b) Tip of the nerve transection device. Notably, the notch of the tip was polished to the sharpness of a knife to cut the sciatic nerve. (c) The device consisted of a 19-gauge guidance needle connected to a 14-gauge needle with fork tips and was inserted at the caudal surface of the ipsilateral thigh through the muscle layers to the sciatic nerve branches. After removal of the guidance head, the fork tips were exposed. A stainless steel wire was threaded through the needle and fixed to the common peroneal and tibial nerves on the notch of the fork tips with a slack noose

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