Fig. 4

MetaCore network built from Fyb (SLAP-130 or ADAP). Fyb is also referred to as SLAP-130 or ADAP. The red circle shows Fyb (SLAP-130 or ADAP). The networks that are associated with Fyb were built using “build networks” in MetaCore, and interactions were visualized. In these networks, Fyb is indirectly related to S6K (p70 S6 kinase). Bcl-10, B-cell CLL/lymphoma 10; CARD11, caspase recruitment domain family member 11; CBM complex, CARD11-Bcl-10-MALT1 signalosome complex; GSK3 alpha, glycogen synthase kinase 3α; GSK3 alpha/beta, glycogen synthase kinase 3α/β; GSK3 beta, glycogen synthase kinase 3β; IKK-gamma, inhibitor of nuclear factor κB kinase subunit γ; MALT1, MALT1 paracaspase; OGT (GlcNAc transferase), O-linked N-acetylglucosamine transferase; p70 S6 kinase, 70 KDa ribosomal protein S6 kinase; p70 S6 kinase 1, 70 KDa ribosomal protein S6 kinase 1; p70 S6 kinase 2, 70 KDa ribosomal protein S6 kinase 2; PP2A regulatory, protein phosphatase 2A; PPP2R2C, protein phosphatase 2 regulatory subunit Bγ; RNPC1, RNA binding motif protein 38 (RNPC1 is previous HGNC symbol for RBM38 gene); Securin, Securin is also referred to as pituitary tumor-transforming 1 (PTTG1); TAK1 (MAP3K7), mitogen-activated protein kinase kinase kinase 7 (TAK1 is previous HGNC symbol for MAP3K7)