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Table 3 Moving distance in the open field test (mean ± SEM, m, n = 10)

From: Baicalin regulates the dopamine system to control the core symptoms of ADHD

Group Week 0 Week 1 Week 2 Week 3 Week 4
WKY + saline 21.66 ± 2.67 19.47 ± 2.24 15.16 ± 2.27 12.55 ± 1.63 9.78 ± 2.75
SHR + saline 43.84 ± 2.39## 42.18 ± 2.03## 40.04 ± 2.35## 39.60 ± 2.22## 40.51 ± 1.79##
SHR + MPH(1.5 mg/kg) 46.34 ± 3.13 26.66 ± 2.67** 21.14 ± 2.30** 17.69 ± 2.46** 12.23 ± 2.22**
SHR + baicalin(50 mg/kg) 45.06 ± 1.48 41.57 ± 1.75 38.89 ± 2.71 29.12 ± 2.57* 23.41 ± 2.87**
SHR + baicalin(100 mg/kg) 44.89 ± 3.42 41.01 ± 2.82 31.64 ± 2.58* 26.77 ± 1.90** 21.19 ± 3.48**
SHR + baicalin(150 mg/kg) 46.48 ± 2.80 33.24 ± 1.75* 24.54 ± 1.63** 17.52 ± 1.76** 14.26 ± 2.83**
  1. Note: Comparison of the moving distance in the open field test in all groups; values are expressed as the mean ± S.E.M. #p < 0.05 and ##p < 0.01 versus WKY + saline group; *p < 0.05 and **p < 0.01 versus SHR + saline group