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Table 4 Moving speed in the open field test (mean ± SEM, cm/s, n = 10)

From: Baicalin regulates the dopamine system to control the core symptoms of ADHD

Group Week 0 Week 1 Week 2 Week 3 Week 4
WKY + saline 7.09 ± 0.68 6.71 ± 1.25 6.00 ± 1.16 4.66 ± 1.03 4.01 ± 1.28
SHR + saline 20.46 ± 1.45## 17.37 ± 0.91## 18.51 ± 1.03## 17.65 ± 1.34## 18.23 ± 1.54##
SHR + MPH(1.5 mg/kg) 18.73 ± 1.07 11.56 ± 1.10** 8.81 ± 1.29** 6.80 ± 1.45** 4.10 ± 1.42**
SHR + baicalin(50 mg/kg) 18.36 ± 1.00 16.75 ± 1.67 15.93 ± 1.50 11.08 ± 0.47* 9.98 ± 1.29**
SHR + baicalin(100 mg/kg) 19.75 ± 1.61 16.54 ± 1.06 10.16 ± 0.89** 8.76 ± 1.17** 5.95 ± 0.72**
SHR + baicalin(150 mg/kg) 18.15 ± 1.14 13.41 ± 0.98* 9.12 ± 1.02** 6.84 ± 1.92** 4.64 ± 1.14**
  1. Note: Comparison of the moving speed in open field test in all groups; values are expressed as the mean ± S.E.M. #p < 0.05 and ##p < 0.01 versus WKY + saline group; *p < 0.05 and **p < 0.01 versus SHR + saline group