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Table 6 Swimming distance in the Morries Water Maze test (mean ± SEM, m, n = 10)

From: Baicalin regulates the dopamine system to control the core symptoms of ADHD

Group

Day1

Day2

Day3

Day4

Day5

WKY + saline

6.00 ± 1.42

4.25 ± 0.85

5.14 ± 1.19

5.98 ± 1.33

5.76 ± 0.68

SHR + saline

13.54 ± 0.83##

11.00 ± 1.06##

9.11 ± 1.20##

9.15 ± 1.05#

9.45 ± 1.12#

SHR + MPH(1.5 mg/kg)

12.96 ± 1.09

8.15 ± 1.12*

4.46 ± 0.90**

3.35 ± 1.14**

3.25 ± 0.91**

SHR + baicalin(50 mg/kg)

12.53 ± 0.88

10.18 ± 0.32

7.76 ± 1.05

4.49 ± 1.14**

5.30 ± 1.39**

SHR + baicalin(100 mg/kg)

11.18 ± 1.04

8.09 ± 1.56*

5.57 ± 1.26**

4.15 ± 1.16**

4.67 ± 1.40**

SHR + baicalin(150 mg/kg)

12.90 ± 0.42

7.22 ± 1.18**

4.42 ± 1.21**

3.25 ± 1.27**

3.15 ± 1.01**

  1. Note: Comparison of the swimming distance in Morries water maze in all groups, values are expressed as the mean ± S.E.M. #p < 0.05 and ##p < 0.01 versus WKY + saline group; *p < 0.05 and **p < 0.01 versus SHR + saline group