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Fig. 1 | Molecular Brain

Fig. 1

From: Gene expression meta-analysis of Parkinson’s disease and its relationship with Alzheimer’s disease

Fig. 1

Workflow of data processing. Outlier samples were removed, and data normalized before the detection (Present/Absent) call algorithm was used to remove data that was not reliably detected. For each study, probesets with absent calls across a chosen percentage of samples were removed. This was repeated in 5% intervals removing probesets with 5% up to 95% of samples absent. The percentage absent cut-off used was set to optimize the normal distribution of the data. After this, the bottom 5% of average expression values across samples was removed and meta-analysis performed

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