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Fig. 2 | Molecular Brain

Fig. 2

From: Proteomics of the corpus callosum to identify novel factors involved in hypomyelinated Niemann-Pick Type C disease mice

Fig. 2

Function analyses of identified proteins. a: The gene ontology cellular compartment term (Go CC) enrichment of identified proteins. The myelin-specific term was labeled in green and neuron-specific terms in red. The number in the bars indicated protein number in each term, the red point marked FDR value presented by its -Log10 value. b: The numbers of identified proteins were compared to the protein data from myelin-enriched fraction reported by Jahn et al. (2009). The numbers of identified major or total myelin proteins were illustrated in white and non-identified in grey. c: The abundance of identified proteins from WT, NPC, and the data derived from myelin-enriched fraction as reported by Jahn et al. (2009). The sums of valid protein abundances from each group were set to 100%. The top 7 proteins from myelin-enriched fraction were labeled individually with different colors. Proteins that not reported from myelin-enriched fraction were labeled in grey

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