Fig. 5

Profiles of food intake and effort-related choice behaviour of mGluR5 KO mice and WT littermates. a Consumption of freely available standard laboratory chow and strawberry milk (given in isolation) were measured for 12 h. WT group n = 10 and mGluR5 KO group n = 10. b Comparison of freely available SM and chow consumption measured for an hour a day for 5 consecutive days under maintained food restriction conditions. WT group n = 6 and mGluR5 KO group n = 6 (Two-way ANOVA, main effect of chow or SM consumption; ***p < 0.001). (c-d) WT group n = 10 and mGluR5 KO group n = 10 were analyzed for ERC performance. c SM consumption across increasing operant work requirements in the ERC task (Two-way RM ANOVA followed by Bonferroni post hoc test, †p = 0.044, †††p < 0.001 between genotypes, ***p < 0.001 compared to the ERC8 condition). d Chow consumption across increasing operant work requirements in the ERC task (Two-way RM ANOVA followed by Bonferroni post hoc test, **p = 0.002, ***p < 0.001 compared to the ERC8 condition). All data are presented as means ± s.e.m