Fig. 1
From: Conditioned stimulus presentations alter anxiety level in fear-conditioned mice
Anxiety measurements during the recall of fear memory. a Experimental procedures. Twenty-four hours after CS+/CS- discriminative fear conditioning, mice were tested on memory retention. They were then divided into three groups with comparable freezing levels. In 48 h, one group was tested for fear memory (n = 10), one tested in shuttle box (n = 10) and the third group on EPM (n = 10). b Freezing levels during fear recall in context B (48 h after fear retention test). c Light time (%) in the shuttle box during CS presentation. d Open arm time on the EPM during CS presentation. e Number of open arm entries on the EPM during CS presentation. *, p < 0.05; **, p < 0.01; ***, p < 0.001. Data were analyzed by One-way RM ANOVA followed by Bonferroni post-test