Fig. 4

Anxiety-like behavior assessment by elevated plus maze test, mice were placed in a plus maze apparatus and allowed to move freely for 5 min. Time in open arms (a and c) and entry number to open arms (b and d) were measured at 2 weeks PS (a and b) or 4 weeks PS (c and d). Unpaired two-tailed t-test was performed. Data are represented as mean ± S.E.M. (n = 24/group at 2 weeks PS, n = 34/group at 4 weeks PS)