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Fig. 1 | Molecular Brain

Fig. 1

From: Identification of a molecular gating determinant within the carboxy terminal region of Cav3.3 T-type channels

Fig. 1

Identification of a conserved region within the carboxyl terminal domain of T-type channels. a Schematic representation of the T-type channel membrane topology and protein sequence alignment of the carboxyl terminal domain of the three T-type channel isoforms (Cav3.1, Cav3.2, and Cav3.3) showing a stretch of highly conserved residues within the proximal region (highlighted in yellow). b Protein sequence alignment of the conserved proximal C-terminal region of Cav3.3 with the C-terminal domain of high-voltage-activated (HVA) calcium channels. Only HVA channels for which some degree of homology exist are shown. Numbers in bracket indicate the percentage of identity and similarity, respectively

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Molecular Brain

ISSN: 1756-6606