Skip to main content
Fig. 1 | Molecular Brain

Fig. 1

From: Identification of a molecular gating determinant within the carboxy terminal region of Cav3.3 T-type channels

Fig. 1

Identification of a conserved region within the carboxyl terminal domain of T-type channels. a Schematic representation of the T-type channel membrane topology and protein sequence alignment of the carboxyl terminal domain of the three T-type channel isoforms (Cav3.1, Cav3.2, and Cav3.3) showing a stretch of highly conserved residues within the proximal region (highlighted in yellow). b Protein sequence alignment of the conserved proximal C-terminal region of Cav3.3 with the C-terminal domain of high-voltage-activated (HVA) calcium channels. Only HVA channels for which some degree of homology exist are shown. Numbers in bracket indicate the percentage of identity and similarity, respectively

Back to article page
\