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Fig. 2 | Molecular Brain

Fig. 2

From: Identification of a molecular gating determinant within the carboxy terminal region of Cav3.3 T-type channels

Fig. 2

Role of C-terminus on Cav3.3 activation. a Representative set of current traces recorded in response to 300 ms depolarizing steps ranging from − 80 mV to 0 mV from a holding potential of − 100 mV from cells expressing the different Cav3.3 channel combinations indicated above the current traces. The red trace indicates the current recorded in response to a depolarization step at − 50 mV. b Corresponding mean normalized voltage dependence of activation. c Corresponding mean half activation potential. d Corresponding mean activation slope factor. e Current-voltage relationships for cells expressing WT (black circles), C short (grey circles), and ΔC (purple circles) channel constructs. f Corresponding mean maximal conductance

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