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Fig. 3 | Molecular Brain

Fig. 3

From: Identification of a molecular gating determinant within the carboxy terminal region of Cav3.3 T-type channels

Fig. 3

Role of C-terminus on Cav3.3 inactivation a Representative set of current traces recorded in response to 300 ms depolarizing step to − 20 mV from a holding potential of − 100 mV, preceded by 15 s inactivating pulse ranging from − 120 mV to − 30 mV from cells expressing the different Cav3.3 channel combinations indicated above the current traces. The red trace indicates the current recorded after an inactivating pulse at − 60 mV. b Corresponding mean normalized voltage dependence of steady state inactivation. c Corresponding mean half inactivation potential. d Corresponding mean steady state inactivation slope factor

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