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Fig. 4 | Molecular Brain

Fig. 4

From: Identification of a molecular gating determinant within the carboxy terminal region of Cav3.3 T-type channels

Fig. 4

Role of C-terminus on Cav3.3 inactivation kinetics. a Representative current traces recorded in response to 1 s depolarizing step to − 20 mV from a holding potential of − 100 mV from cells expressing the different Cav3.3 channel combinations indicated above. The dotted red line indicates the fit of the current decay by a single (WT, C short, and ΔC + CD4-C) or double exponential function (ΔC). The grey line represents the WT current for comparison. b Corresponding mean time constant of inactivation. c Corresponding mean fractions of inactivating and non-inactivating current

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