Fig. 1

Expressions of Cdh9 and Cdh11 in neonatal cerebellum. In situ hybridization of Cdh9 and Cdh11 mRNAs was performed on serial sagittal sections of two different brains at P4. Sagittal levels of the cerebellum are defined as follows: S0 is the most lateral sagittal level, and S10 is the most medial section of the cerebellum. a-e sections show Cdh9 expression signals and f-j sections show Cdh11 expression signals at different sagittal levels. In general, Cdh9 is expressed in more medial levels and in multiple lobules, whereas Cdh11 is highly expressed in most lateral levels, including Crus I (CI) and Crus II (CII), and its expression is restricted to a narrow band in lobules VI/VII of the vermis. These data show that Cdh9 and Cdh11 are expressed in the Purkinje cell layer in different domains of the cerebellum. C1: Crus I; CII: Crus II; S: Simple lobule; PM: Paramedian lobule; PFL: Paraflocculus. Scale: 500 μm