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Fig. 6 | Molecular Brain

Fig. 6

From: Segregated expressions of autism risk genes Cdh11 and Cdh9 in autism-relevant regions of developing cerebellum

Fig. 6

Delayed dendritic development of Purkinje cells in lobules VI/VII at P10. In situ hybridization followed by calbindin staining was performed on P10 sagittal sections. a, b shows an example sagittal section from the vermis. a In situ hybridization signals of Cdh11. Arrows mark the central area of lobules VI/VII with Cdh11 mRNA expression. b Counterstaining of calbindin on the same section shows the general morphology of Purkinje cells. Arrows mark the same area of lobules VI/VII in (a). c, e and g are enlarged images of parts of lobules IV, V, and VIII, respectively, from (b). d, f and h are enlarged images of parts of lobules VIa, VIb, and VII, respectively, from (b). Arrows indicate that lobules VIa, VIb, and VII have a much thinner molecular layer than that of lobules IV, V, and VIII. Scale bars: 200 μm

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