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Fig. 2 | Molecular Brain

Fig. 2

From: Predictable chronic mild stress promotes recovery from LPS-induced depression

Fig. 2

PCMS mitigates LPS-induced neuroinflammation. Relative mRNA expression of the proinflammatory cytokines, IL-1β (a), IL-6 (b), and TNF-α (c) in the hippocampus of mice brain 6 h and 26 h after saline or LPS (500 μg/kg) treatment. Histological changes and microglial activation (Iba-1 immunofluorescence) in the hippocampal CA1 region (d). Scale bar = 50 μm. Data are means ± SEM (n = 7). *p < 0.05, **p < 0.01 compared with the saline-treated naive group. ##p < 0.01 compared with the corresponding LPS group

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