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Fig. 4 | Molecular Brain

Fig. 4

From: Predictable chronic mild stress promotes recovery from LPS-induced depression

Fig. 4

PCMS ameliorates LPS-induced NLRP3 overexpression. Relative mRNA expression of NLRP3 (a), ASC (b), and caspase-1 (c). Representative blots of NLRP3 and inflammasome components (ASC and caspase-1 P20) and mature IL-1β (d). Statistical graphs of relative protein expression of NLRP3 (e), ASC (f), and caspase-1 P20 (g). The immunostaining images of IL-1β in the hippocampal CA1 region (h). Scale bar = 50 μm. Data are means ± SEM (n = 6). *p < 0.05, **p < 0.01 compared with the saline-treated naive group. #p < 0.05, ##p < 0.01 compared with the corresponding LPS group

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