Fig. 5
From: Predictable chronic mild stress promotes recovery from LPS-induced depression
PCMS alleviates LPS-induced impairment of Nrf2-TXNIP-Trx signaling. Relative mRNA expression of Nrf2 (a) and Nrf2-downstream antioxidant genes HO-1 (b), and NQO-1 (c). Immunofluorescence staining images of Nrf2 in the hippocampal CA1 region (d). Representative blots (e) and statistical graphs of relative protein expression of Nrf2 (f), HO-1 (g), NQO-1 (h), TXNIP (i), and Trx (j). Scale bar = 50 μm. Data are means ± SEM (n = 6). *p < 0.05, **p < 0.01 compared with the saline-treated naive group. #p < 0.05, ##p < 0.01 comparedwith the corresponding LPS group