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Table 2 Candidate miRNAs for qPCR identified in microarray analysis

From: Identification of plasma microRNA expression changes in multiple system atrophy and Parkinson’s disease

 

Normalized Value (Average ± S.E.)

Fold Change

p-value

MSA

Control

MSA/Control

Kruskal-Wallis test

Up-regulated miRNAs

hsa-miR-371b-5p

126.33 ± 33.77

25.55 ± 1.53

4.945

0.012

hsa-miR-4708-3p

48.86 ± 11.45

18.78 ± 1.94

2.602

0.010

hsa-miR-4736

25.26 ± 1.86

15.49 ± 1.65

1.631

0.006

hsa-miR-663a

1126.09 ± 106.97

775.23 ± 43.51

1.453

0.025

Down-regulated miRNAs

hsa-miR-15b-5p

122.50 ± 25.56

449.37 ± 152.38

0.273

0.010

hsa-miR-3622b-5p

85.63 ± 26.38

249.39 ± 30.05

0.343

0.008

hsa-miR-19b-3p

150.93 ± 24.73

431.39 ± 146.55

0.350

0.010

hsa-miR-920

135.44 ± 27.54

297.63 ± 26.84

0.455

0.008

hsa-miR-671-5p

172.23 ± 36.23

361.45 ± 63.47

0.476

0.008

hsa-miR-4722-5p

91.16 ± 10.91

172.25 ± 14.11

0.529

0.003

hsa-miR-24-3p

482.25 ± 63.88

888.09 ± 44.05

0.543

0.002

hsa-miR-149-3p

573.56 ± 90.68

1025.11 ± 82.38

0.560

0.008

hsa-miR-4728-5p

112.43 ± 11.72

189.34 ± 13.59

0.594

0.003

hsa-miR-3162-5p

155.65 ± 14.27

261.60 ± 29.02

0.595

0.006

hsa-miR-4270

132.64 ± 17.07

214.49 ± 9.16

0.618

0.006

hsa-miR-4667-5p

89.86 ± 5.61

144.17 ± 5.63

0.623

0.001

hsa-miR-4726-5p

116.39 ± 8.44

181.47 ± 7.01

0.641

< 0.001

  1. MSA multiple system atrophy, S.E. standard error
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Molecular Brain

ISSN: 1756-6606