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Table 4 Top 15 statistically significant GO processes relevant to the top 50 predicted target genes of hsa-miR-671-5p

From: Identification of plasma microRNA expression changes in multiple system atrophy and Parkinson’s disease

 

GO processes

p-value

FDR

1

regulation of vascular smooth muscle contraction

5.47E-12

1.95E-08

2

positive regulation of smooth muscle contraction

7.63E-11

1.36E-07

3

positive regulation of muscle contraction

1.69E-09

2.01E-06

4

regulation of neuron differentiation

3.71E-09

2.38E-06

5

positive regulation of neuron differentiation

3.75E-09

2.38E-06

6

nervous system development

4.14E-09

2.38E-06

7

phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway

4.67E-09

2.38E-06

8

regulation of system process

6.77E-09

2.77E-06

9

saliva secretion

7.77E-09

2.77E-06

10

adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway

7.77E-09

2.77E-06

11

secretion by tissue

1.43E-08

4.55E-06

12

regulation of blood circulation

1.53E-08

4.55E-06

13

regulation of muscle contraction

2.27E-08

5.66E-06

14

negative regulation of catecholamine secretion

2.33E-08

5.66E-06

15

regulation of smooth muscle contraction

2.39E-08

5.66E-06

  1. GO gene ontology, FDR false discovery rate