Fig. 4
From: Ankyrin B and Ankyrin B variants differentially modulate intracellular and surface Cav2.1 levels
AnkB and its variants increase peak current density. HEK293T cells were co-transfected with Cav2.1, α2δ1, β4, and GFP control, wildtype, or mutant AnkB-GFP. (a) Peak current density was determined by dividing the peak current by whole cell capacitance. One-way ANOVA followed by Dunnett’s multiple comparison, F(4,151) = 6.465, p < 0.0001 (b) Normalized G/Gmax vs. voltage curve fitted using Boltzmann’s equation. One-way ANOVA F(4, 50) = 0.0022, p > 0.9999. This data is included in the MSc thesis of CSWC, University of Victoria, 2019 found at https://dspace.library.uvic.ca//handle/1828/11053