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Fig. 2 | Molecular Brain

Fig. 2

From: Expression of the RNA methyltransferase Nsun5 is essential for developing cerebral cortex

Fig. 2

Nsun5 deficiency impairs development of cerebral cortex. a & b Body weights and pictures of entire brain of PND10 WT mice (WT) and Nsun5-KO mice (KO). Scale bars, 1 mm. c Representative images of cerebral cortex stained with toluidine blue. Scale bars, 100 μm. d Bar graph shows the thickness of layers I-VI. *P < 0.05 vs. WT mice (Student’s t test). e Higher power views of the boxed areas in Fig. c. Scale bars, 50 μm. Representative images of pyramidal cells (arrows) are shown in the bottom right insets. The open arrows indicate the processes and branches of pyramidal cells. Bar graph shows the length of the apical dendrite of pyramidal cells in the layer V. *P < 0.05 vs. WT mice (Student’s t test)

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