Fig. 6
From: Expression of the RNA methyltransferase Nsun5 is essential for developing cerebral cortex
Nsun5 deficiency affects the laminar organization of cortical neurons. a-c Representative images of immunostaining for Tbr1, Ctip2 with DAPI or Stab2 in E18.5 WT mice (WT) and Nsun5-KO mice (KO). Scale bars, 50 μm. Bar graphs show the numbers of Tbr1+ cells in layer VI, Ctip2+ cells in layer V and Stab2+ cells in layers II/III. *P < 0.05 and **P < 0.01 vs. WT mice. d Coronal sections of cerebral cortices stained with toluidine blue in E18.5 WT mice and Nsun5-KO mice. Scale bars, 50 μm. Bar graph shows the total cortical thickness and CP. *P < 0.05 vs. WT mice