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Fig. 6 | Molecular Brain

Fig. 6

From: Anterior insular cortex mediates hyperalgesia induced by chronic pancreatitis in rats

Fig. 6

Enhanced AMPAR and NMDAR currents within aIC after TNBS treatment. a: The AMPAR-mediated synaptic input-output curve of CP rats (n = 11) was steeper than that from sham rats (n = 7), one-way repeated ANOVA. b: The NMDAR-mediated synaptic input-output curve of CP rats (n = 9) was steeper than that from sham rats (n = 10), one-way repeated ANOVA. c: I-V curves of AMPAR-EPSCs of aIC pyramidal neurons recorded at holding potentials ranging from − 60 to + 50 mV in sham and CP rats, one-way repeated ANOVA. d: Comparison of the rectification index of AMPAR-EPSCs in sham (n = 11) and CP (n = 10) rats, unpaired t-test. e: I-V curves of NMDAR-EPSCs of aIC pyramidal neurons recorded at holding potentials ranging from − 60 to + 50 mV in sham and CP rats, one-way repeated ANOVA. f: Comparison of the rectification index of NMDAR-EPSCs in sham (n = 9) and CP (n = 12) rats, unpaired t-test. * P < 0.05, ** P < 0.01, TNBS vs sham

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