Fig. 8
From: Anterior insular cortex mediates hyperalgesia induced by chronic pancreatitis in rats
Bilateral microinjection of CNQX and AP-5 within aIC alleviates visceral hypersensitivity of CP rats. a: The schematic diagram of the behavioral experiment. b: A representative coronal section showing the sites of cannula implantation within bilateral aIC. Bar = 1 mm. c: Bilateral microinjections of CNQX and AP-5, instead of saline, significantly enhanced the AWT in CP rats on POD 14. n = 5 in saline and CNQX-treated groups and 6 in AP5-treated group, one-way ANOVA, * P < 0.05, ** P < 0.01, CNQX or AP5 vs saline