Fig. 5
From: FGF receptors are required for proper axonal branch targeting in Drosophila
– Specific axonal targeting errors are phenocopied in FGF ligand and FGFR mutants. a The FGF ligands Bnl and Pyr bind to their respective FGFRs Btl and Htl at the cell surface. b-f Representative examples of a wildtype axonal arbor (b), Btl RNAi (c), Bnl RNAi (d), Htl RNAi (e) and Pyr RNAi (f) are shown. g Five error types had significantly greater frequency of occurrence in both Btl RNAi and Bnl RNAi mutants compared to wildtype flies. Two targeting error phenotypes had a significantly higher frequency of occurrence (p < 0.05) in the Bnl RNAi mutants than in Btl RNAi mutants. h Pyr RNAi mutants also had five error types that occurred at significantly greater frequency than in wildtype flies that were also found in Htl RNAi mutants. Scale bar is 50 μm. Arrowheads point to absent branches, arrows point to ectopic branches