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Fig. 4 | Molecular Brain

Fig. 4

From: Behavioral analysis in mice deficient for GAREM2 (Grb2-associated regulator of Erk/MAPK subtype2) that is a subtype of highly expressing in the brain

Fig. 4

GAREM2 KO mice showed hyper exploratory activity and low novelty-induced anxiety in the open field test. Total distance travelled, time spent in the center area, and the number of rearing incidents for the total duration (120 min) were analyzed in the open field test. a The change of the total distance travelled (cm) for each genotype. b The change of the time spent in the center area (sec) for each genotype. c The change of the number of rearing behaviors (times) for each genotype. d-g Graphs showing the number of rearing behaviors, time spent in the center area, distance travelled, and anxiety index for GAREM2 KO and WT mice in the analysis of the first 15 min. Anxiety index (=center time / distance travelled). N = 16 for each genotype, error bars indicate SEM

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