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Fig. 5 | Molecular Brain

Fig. 5

From: Proteomic profiling of the neurons in mice with depressive-like behavior induced by corticosterone and the regulation of berberine: pivotal sites of oxidative phosphorylation

Fig. 5

The variation of protein expression after administration of corticosterone (CORT) and berberine (BBR) indicating the correlation to mitochondrion. a Genes of the proteins detected suppressed by CORT but reversed to normal level by BBR compared with normal control. b Genes of the proteins suppressed by CORT but increased in higher level distinctly by BBR compared with normal control. c Schematic of the sites of BBR for oxidative phosphorylation in mitochondria respiratory chain based on the Functional Annotation Chart of David Bioinformatics Resources 6.8 (https://david.ncifcrf.gov/). d Networks of Uqcc2 to NADH dehydrogenases based on String: Functional protein associated networks (https://string-db.org/). “Red triangle”: Target of BBR action

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Molecular Brain

ISSN: 1756-6606