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Fig. 6 | Molecular Brain

Fig. 6

From: Silencing of microRNA-146a alleviates the neural damage in temporal lobe epilepsy by down-regulating Notch-1

Fig. 6

Cell apoptosis in CA1 and CA3 regions of hippocampus in rats detected by TUNEL (N = 5). Model, temporal lobe epilepsy (TLE) rats; Control, normal rats; microRNA-146a (miRNA-146a), TLE rats transfected with miRNA-146a siRNA; miRNA-146a negative control (miRNA-146a NC), TLE rats transfected with miRNA-146a NC. a microscopic observation of apoptotic cells in CA1 region; b) the number of apoptotic cells in stratum pyramidale of CA1 region; c) microscopic observation of apoptotic cells in CA3 region; d) the number of apoptotic cells in stratum pyramidale of CA3 region. *, P < 0.05 vs. Control group; #, P < 0.05 vs. Model group

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Molecular Brain

ISSN: 1756-6606