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Fig. 6 | Molecular Brain

Fig. 6

From: Differential regulation of Cav2.2 channel exon 37 variants by alternatively spliced μ-opioid receptors

Fig. 6

Inhibition of Src and Cav2.2-37a Y1747F abolish the effect of mMOR1C on Cav2.2-37a peak current density. a Peak current density of Cav2.2-37a channels treated overnight with vehicle (0.1% water or 500 ng/ml of PTX overnight. b Peak current density of Cav2.2-37a channels treated for 4 h with vehicle (0.004% DMSO) or 2 μM of the Src inhibitor PP1. c Peak current density of the Cav2.2-37a Y1747F mutant in the absence and the presence of mMOR1C. The number of cells recorded is indicated in parentheses, asterisks denote significance at the *0.05 and **0.01 levels (a and b – ANOVA, c - Mann-Whitney test)

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