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Fig. 2 | Molecular Brain

Fig. 2

From: Restoring Wnt/β-catenin signaling is a promising therapeutic strategy for Alzheimer’s disease

Fig. 2

Restoring Wnt/β-catenin signaling is a promising therapeutic strategy for AD. Wnt/β-catenin signaling is able to regulate multiple different pathways in Alzheimer disease (AD) pathogenesis. Restoring Wnt/β-catenin signaling in the brain of the AD patients will enhance synaptic plasticity, neuronal survival, neurogenesis and BBB integrity and function and suppress Aβ production and tau phosphorylation. The role of Wnt/β-catenin signaling in neuroinflammation remains to be elucidated

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