Fig. 4

Prediction of hippocampal gene expression from peripheral blood metabolome. a Genes processed for this prediction analysis were provided from a previous study by Hagihara et al. [14]. The correlation coefficients between actual and predicted expression levels of each gene are shown. Dashed lines indicatea a P-value of 0.05 and asterisks indicates significant correlations after Bonferroni correction for multiple testing (significance level: P < 0.00714 = 0.05/7). b Scatter plot showing significant correlations between actual and predicted expression level of Arntl. The correlation was not due to outliers. c Feature preference for constructing the prediction model of Arntl expression level. d Results of pathway enrichment analysis for the metabolites used for constructing the prediction model of Arntl expression level. The statistical enriched terms with raw P-value below 0.05 are shown