Gene name | Alias | Tissue/ Subcellular localization | Neurological disease | Expression levels in the progression of AD |
---|---|---|---|---|
SLC30A1 | ZnT1 | Dendritic spines, synaptic membranes [12] | Alzheimer’s Disease [53] | |
SLC30A3 | ZnT3 | Hippocampus, cortex [54] | Alzheimer’s Disease [19], Learning deficit and memory loss [18] | Decreased [19] |
SLC30A4 | ZnT4 | Endosomal/secretory vesicles [53] | Alzheimer’s Disease [55] | Increased [55] |
SLC30A5 | ZnT5 | Golgi apparatus [48] | Alzheimer’s Disease [56] | Unknown |
SLC30A6 | ZnT6 | Golgi apparatus [48] | ||
SLC30A7 | ZnT7 | Golgi apparatus [58] | Alzheimer’s Disease [56] | Increased [59] |
SLC30A10 | ZnT10 | Brain and liver [14] | Parkinson’s Disease [49] Alzheimer’s Disease [60] | Decreased [60] |
SLC39A1 | ZIP1 | Hippocampus, thalamus [15] | Alzheimer’s Disease [61] | Increased [61] |
SLC39A3 | ZIP3 | Hippocampus pyramidal neurons [62] | Seizure-induced CA1degeneration [62] | Unknown |
SLC39A4 | ZIP4 | Choroid plexus [15] | Glioma [63] | Unknown |
SLC39A6 | ZIP6 | Hippocampal pyramidal apical membrane of choroid plexus [17] | Unknown | Unknown |
SLC39A9 | ZIP9 | Trans-Golgi network [64] | Unknown | Unknown |
SLC29A13 | ZIP13 | Golgi apparatus [14] | SCD-EDS [65] | Unknown |