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Fig. 2 | Molecular Brain

Fig. 2

From: Sinomenine inhibits amyloid beta-induced astrocyte activation and protects neurons against indirect toxicity

Fig. 2

ADDL-induced increase in nitric oxide level in astrocytic cells is inhibited by sinomenine. The C8D1A astrocytic cells were treated with oligomeric amyloid beta (ADDL) in the absence or presence of sinomenine and the levels of nitric oxide (NO) were assessed. ADDL treatment increased NO level in the cells. However, sinomenine inhibited the ADDL-induced increase in the NO level (n = 4). Sinomenine did not affect NO level in the cells in the absence of ADDL treatment. Asterisk indicates significant difference from control (p < 0.05). # indicates significant difference (p < 0.05) between groups as indicated

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