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Fig. 2 | Molecular Brain

Fig. 2

From: Diverged morphology changes of astrocytic and neuronal primary cilia under reactive insults

Fig. 2

Regional cilia length variations in the hippocampal CA1, CA3 and DG in Arl mice, FVB/N and C57BL/6 mice. a Arl13b-positive cilia in hippocampal regions of Arl mice were significantly shorter cilia in the DG than in CA1 or CA3 (***, p < 0.001, unpaired Student’s t-test). N = 8 mice. Cilia number: 399, 230, and 435. b Arl13b-positive cilia of FVB/N mice had no significant differences in length among hippocampal CA1, CA3, and DG regions. N = 5 mice. Cilia number: 213, 146, and 254. c Arl13b-positive cilia of C57BL/6 mice had no significant differences in length among the hippocampal CA1, CA3, and DG regions. N = 4 mice. Cilia number: 144, 118, and 116. d AC3-positive cilia in the hippocampal DG region of Arl mice were significantly (***, p < 0.001) shorter than in the CA1 and CA3 regions, and significantly shorter in the CA3 than in the CA1 (*, p < 0.05). N = 4 mice. Cilia number: 403, 471, and 527. e AC3-positive cilia in hippocampal DG regions of FVB/N control mice were significantly (***, p < 0.001) shorter than in the CA1 and CA3 regions. N = 5 mice. Cilia number: 386, 343, and 555. f AC3-positive cilia in hippocampal DG regions of C57BL/6 mice were significantly (***, p < 0.001) shorter than in the CA1 and CA3 regions. N = 4. Cilia number: 202, 422, and 180. Data were analyzed with one-way ANOVA with post hoc Tukey test. Arl13b: Arl strain: F(2, 1061) = 11.05, p < 0.001; FVB: F(2, 610) = 0.5850, p = 0.4632; C57BL/6: F(F(2, 3775) = 0.7700, p = 0.4632; AC3: Arl Strain: F(2, 1398) = 213.6, p < 0.001; FVB: F(2, 1281) = 93.82, p < 0.001; C57BL/6: F(2, 801) = 62.96, p < 0.001

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